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Details on Person UniProt:Q9VND8 Rheb
Class:Id
ReferenceGeneProduct:99975
_chainChangeLog
chain:1-179 added on Sat February 7 2015;propeptide:180-182 added on Sat February 7 2015
_displayName
UniProt:Q9VND8 Rheb
_timestamp
2025-02-21 19:42:26
chain
chain:1-179 propeptide:180-182
checksum
CAB8AE2A988A0179
comment
FUNCTION Binds GTP and exhibits intrinsic GTPase activity (By similarity). Activates the protein kinase activity of TORC1, and thereby plays a role in the regulation of apoptosis (PubMed:22493059). Stimulates the phosphorylation of S6K through activation of TORC1 signaling (PubMed:22493059). May also have a role in activating TORC2 signaling (PubMed:22493059).CATALYTIC ACTIVITY GTP + H2O = GDP + phosphate + H(+)INTERACTION Belongs to the small GTPase superfamily. Rheb family.
description
recommendedName: GTP-binding protein Rheb homolog ecNumber evidence="2"3.6.5.-
