Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person ALYREF recruits DDX39B

Class:IdReaction:9991393
_displayNameALYREF recruits DDX39B
_doReleaseFALSE
_timestamp2026-06-04 17:50:43
authored[InstanceEdit:9991319] Stephan, Ralf, 2026-05-27
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9991336] Stephan, Ralf, 2026-06-04
disease[Disease:3134794] viral infectious disease
input[Complex:9991359] ORF57:mRNA:CBC:ALYREF [nucleoplasm] [Homo sapiens]
[Complex:8849161] DDX39B:ATP [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9991360] Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication
[LiteratureReference:9991327] An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export
[LiteratureReference:8849119] Recruitment of the human TREX complex to mRNA during splicing
nameALYREF recruits DDX39B
output[Complex:9991363] ORF57:mRNA:CBC:ALYREF:DDX39B(ATP) [nucleoplasm] [Homo sapiens]
relatedSpecies[Species:2671781] Human herpesvirus 8
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9991485] R-HSA-9991393.1
summation[Summation:9991409] ORF57 bound to HHV8 intronless mRNA engages the export adapt...
(hasEvent)[Pathway:9991330] Export of HHV8 transcripts from nucleus [Homo sapiens]
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No pathways have been reviewed or authored by ALYREF recruits DDX39B (9991393)