Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person HHV8 ORF45 binds NLRP1

Class:Id	Reaction:9989216
_displayName	HHV8 ORF45 binds NLRP1
_doRelease	FALSE
_timestamp	2026-05-19 13:17:18
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9989214] Shamovsky, Veronica, 2026-05-19
input	[EntityWithAccessionedSequence:9973353] ORF45 [cytosol] [Human herpesvirus 8] [Complex:9988939] NLRP1(1-1212):NLRP1(1213-1473) [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9989208] KSHV-encoded ORF45 activates human NLRP1 inflammasome
name	HHV8 ORF45 binds NLRP1
output	[Complex:9989212] NLRP1(1-1212):ORF45 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9988926] NLRP1(1213-1473) [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9988948] Autoproteolysis of NLRP1 [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9989220] R-HSA-9989216.1
summation	[Summation:9989204] The Kaposi’s sarcoma-associated herpesvirus (KSHV) tegument ...
(hasEvent)	[Pathway:9988947] The NLRP1 inflammasome (to replace 844455) [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by HHV8 ORF45 binds NLRP1 (9989216)