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Details on Person Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding

Class:IdLiteratureReference:9988929
_displayNameHuman DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
_timestamp2026-05-14 01:57:09
author[Person:6813831] Zhong, Franklin L
[Person:9988907] Robinson, Kim
[Person:9988932] Teo, Daniel Eng Thiam
[Person:9988990] Tan, Kiat-Yi
[Person:9988999] Lim, Chrissie
[Person:9988950] Harapas, Cassandra R
[Person:9988937] Yu, Chien-Hsiung
[Person:9988896] Xie, William H
[Person:9686095] Sobota, Radoslaw M
[Person:9988952] Au, Veonice Bijin
[Person:9988961] Hopkins, Richard
[Person:9988958] D'Osualdo, Andrea
[Person:5357762] Reed, John C
[Person:9988910] Connolly, John E
[Person:9686140] Masters, Seth L
[Person:508090] Reversade, Bruno
created[InstanceEdit:9988942] Shamovsky, Veronica, 2026-05-14
journalJ Biol Chem
pages18864-18878
pubMedIdentifier30291141
titleHuman DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
volume293
year2018
(literatureReference)[Reaction:9988924] DPP9 binds autoinhibited full-length NLRP1 [Homo sapiens]
[Reaction:9988956] DPP9:NLRP1 binds the C-terminal fragment of NLRP1 [Homo sapiens]
[Summation:9988914] The active C-terminal (CT) fragment of NLRP1, consisting of ...
[Summation:9988981] A dipeptidyl peptidases DPP9 (and/or DPP8) binds one molecul...
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