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Details on Person Signal Peptidase (Canis) cleaves the signal peptide of Preprolactin

Class:IdReaction:9988754
_displayNameSignal Peptidase (Canis) cleaves the signal peptide of Preprolactin
_timestamp2026-05-13 00:44:28
catalystActivity[CatalystActivity:445314] serine-type endopeptidase activity of Signal Peptidase Complex (Canis familiaris) [endoplasmic reticulum membrane]
catalystActivityReference[CatalystActivityReference:9643235] serine-type endopeptidase activity of Signal Peptidase Complex (Canis familiaris) [endoplasmic reticulum membrane] Purification of microsomal signal peptidase as a complex
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:9988755] May, Bruce, 2026-05-12
input[Complex:445264] Preprolactin:Translocon:TRAP [endoplasmic reticulum membrane] [Bos taurus]
isChimericTRUE
literatureReference[LiteratureReference:445307] Purification of microsomal signal peptidase as a complex
[LiteratureReference:9988652] Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity
modified[InstanceEdit:9988893] May, Bruce, 2026-05-13
nameSignal Peptidase (Canis) cleaves the signal peptide of Preprolactin
output[Complex:9988758] Prolactin (bovine):Sec61 translocon (canine):TRAP [endoplasmic reticulum membrane] [Bos taurus]
[EntityWithAccessionedSequence:9988759] Prolactin signal peptide(Bos taurus) [endoplasmic reticulum membrane] [Bos taurus]
species[Species:48898] Bos taurus
[Species:49646] Canis familiaris
stableIdentifier[StableIdentifier:9988770] R-NUL-9988754.1
summation[Summation:445303] The signal peptide is cleaved by the signal peptidase comple...
(inferredFrom)[Reaction:9988102] Signal peptidase cleaves signal peptide from nascent polypeptide during translation [Homo sapiens]
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