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Details on Person At the HHV8 terminal repeats in the nucleoplasm, LANA-bound ...
| Class:Id | Summation:9988664 |
|---|---|
| _displayName | At the HHV8 terminal repeats in the nucleoplasm, LANA-bound ... |
| _timestamp | 2026-05-10 17:35:41 |
| created | [InstanceEdit:9988656] Stephan, Ralf, 2026-05-10 |
| text | At the HHV8 terminal repeats in the nucleoplasm, LANA-bound PCNA serves as a sliding clamp that recruits DNA polymerase δ (POLD) and DNA polymerase ε (POLE) to the viral episome (Strzalka and Ziemienowicz, 2011). The presence of PCNA at the TR is supported by LANA-dependent recruitment of the cellular DNA polymerase clamp loader and other replication factors (Losay and Damania, 2025), and ChIP assays demonstrated that DNA polymerase δ is selectively enriched at the TR during S phase in a LANA-dependent manner (Dheekollu et al. 2013). |
| (summation) | [Reaction:9988614] PCNA recruits DNA polymerase δ/ε [Homo sapiens] |
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No pathways have been reviewed or authored by At the HHV8 terminal repeats in the nucleoplasm, LANA-bound ... (9988664)
