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Details on Person PHF6 binds SWI/SNF complexes

Class:IdReaction:9988507
_displayNamePHF6 binds SWI/SNF complexes
_doReleaseTRUE
_timestamp2026-05-14 18:47:40
authored[InstanceEdit:9988500] Rothfels, Karen, 2026-05-07
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9988508] Rothfels, Karen, 2026-05-07
edited[InstanceEdit:9988500] Rothfels, Karen, 2026-05-07
input[CandidateSet:9988499] pBAF, ncBAF [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:9941736] PHF6 [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9989056] Gillespie, Marc E, 2026-05-14
isChimericFALSE
literatureReference[LiteratureReference:9988408] Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair
[LiteratureReference:9988467] Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting
[LiteratureReference:9988488] PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression
[LiteratureReference:9988384] PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
[LiteratureReference:9941731] PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex
[LiteratureReference:9941724] Structural basis of plant homeodomain finger 6 (PHF6) recognition by the retinoblastoma binding protein 4 (RBBP4) component of the nucleosome remodeling and deacetylase (NuRD) complex
[LiteratureReference:9988478] PHF6 Degrees of Separation: The Multifaceted Roles of a Chromatin Adaptor Protein
modified[InstanceEdit:9989057] Rothfels, Karen, 2026-05-14
namePHF6 binds SWI/SNF complexes
output[Complex:9988502] PHF6:pBAF, ncBAF [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2026-06-17
reviewed[InstanceEdit:9989054] Pham, Lan, 2026-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9988509] R-HSA-9988507.1
summation[Summation:9988506] PHF6 is a nucleolar and chromatin-associated PHD finger prot...
(hasEvent)[Pathway:9932451] SWI/SNF chromatin remodelers [Homo sapiens]
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