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Details on Person D'Eustachio, Peter, 2026-04-27
| Class:Id | InstanceEdit:9987742 |
| _displayName | D'Eustachio, Peter, 2026-04-27 |
| _timestamp | 2026-04-27 21:30:09 |
| author | [Person:140934] D'Eustachio, Peter |
| dateTime | 2026-04-27 21:29:57 |
| (created) | [DatabaseIdentifier:9987740] RHEA:50052 [DatabaseIdentifier:9987741] RHEA:50056 [DatabaseIdentifier:9987743] RHEA:47101 [ReferenceMolecule:9987744] (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) [ChEBI:77251] [ReferenceMolecule:9987745] 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) [ChEBI:58507] [ReferenceMolecule:9987746] 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) [ChEBI:87704] [DatabaseIdentifier:9987747] RHEA:50064 [ReferenceMolecule:9987748] (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA(4-) [ChEBI:59807] [DatabaseIdentifier:9987749] RHEA:16867 [DatabaseIdentifier:9987750] RHEA:46729 |
| (modified) | [SimpleEntity:159422] TCDCA [cytosol] [CatalystActivity:191973] racemase and epimerase activity of AMACR [peroxisomal matrix] [Reaction:192033] 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one [Homo sapiens] [CatalystActivity:192037] oxidoreductase activity, acting on NAD(P)H as acceptor of CYP27A1 [mitochondrial matrix] [Reaction:192051] CYP7A1 7-hydroxylates CHOL [Homo sapiens] [Reaction:192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA [Homo sapiens] [Reaction:192061] CYP46A1 24-hydroxylates CHOL [Homo sapiens] [Reaction:192067] 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one [Homo sapiens] [SimpleEntity:192096] 25(R) THCA-CoA [cytosol] [Reaction:192097] 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one [Homo sapiens] |
| (structureModified) | [Reaction:192051] CYP7A1 7-hydroxylates CHOL [Homo sapiens] [Reaction:192178] CYP39A1 7-hydroxylates 24OH-CHOL [Homo sapiens] [Reaction:192312] Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate [Homo sapiens] [Reaction:193362] ABCB11 transports bile salts from cytosol to extracellular region [Homo sapiens] [Reaction:193385] Hydrolysis of choloyl-CoA to cholate and CoASH [Homo sapiens] [Reaction:193491] Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate [Homo sapiens] |
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No pathways have been reviewed or authored by D'Eustachio, Peter, 2026-04-27 (9987742)