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Details on Person D'Eustachio, Peter, 2026-04-13

Class:IdInstanceEdit:9987322
_displayNameD'Eustachio, Peter, 2026-04-13
_timestamp2026-04-13 17:17:21
author[Person:140934] D'Eustachio, Peter
dateTime2026-04-13 17:17:16
(created)[Complex:9987315] SREBP1A,2,NF-Y [nucleoplasm] [Homo sapiens]
[CatalystActivity:9987316] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2 dimer [nucleoplasm]
[CatalystActivity:9987317] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y,SP1 [nucleoplasm]
[CatalystActivityReference:9987318] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,2,NF-Y [nucleoplasm] SREBP-2 and NF-Y are involved in the transcriptional regulation of squalene epoxidase
[CatalystActivityReference:9987319] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y [nucleoplasm] Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase
[CatalystActivityReference:9987320] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y [nucleoplasm] Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells
[CatalystActivity:9987321] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,2,NF-Y [nucleoplasm]
[Complex:9987323] SREBP1A,1C,2,NF-Y,SP1 [nucleoplasm] [Homo sapiens]
[CatalystActivityReference:9987324] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y,SP1 [nucleoplasm] Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase
[StableIdentifier:9987325] R-HSA-9987315.1
List all 11 refering instances
(modified)[BlackBoxEvent:1655823] Expression of Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) [Homo sapiens]
[BlackBoxEvent:1655824] Expression of Farnesyl Diphosphate Synthase (FDPS) [Homo sapiens]
[BlackBoxEvent:1655826] Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) [Homo sapiens]
[BlackBoxEvent:1655827] Expression of 7-Dehydrocholesterol Reductase (DHCR7) [Homo sapiens]
[BlackBoxEvent:1655828] Expression of Lanosterol Synthase (LSS) [Homo sapiens]
[BlackBoxEvent:1655830] Expression of Acetyl CoA Carboxylase 2 (ACACB, ACC2) [Homo sapiens]
[BlackBoxEvent:1655832] Expression of Geranylgeranyl Pyrophosphate Synthase (GGPS1) [Homo sapiens]
[BlackBoxEvent:1655833] Expression of TM7SF2 [Homo sapiens]
[BlackBoxEvent:1655835] Expression of ELOVL6 [Homo sapiens]
[BlackBoxEvent:1655836] Expression of Diphosphomevalonate Decarboxylase (MVD) [Homo sapiens]
List all 27 refering instances
(structureModified)[Reaction:2426146] SREBP1A,1C,2 binds the FDFT1 promoter [Homo sapiens]
[Reaction:2426147] SREBP1A,1C,2 binds the FDPS promoter [Homo sapiens]
[Reaction:2426149] SREBP1A,1C,2 binds the ELOVL6 promoter [Homo sapiens]
[Reaction:2426150] SREBP1A,1C,2 binds the HMGCS1 promoter [Homo sapiens]
[Reaction:2426151] SREBP1A,2 binds the SQLE promoter [Homo sapiens]
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No pathways have been reviewed or authored by D'Eustachio, Peter, 2026-04-13 (9987322)
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