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Details on Person DNA-binding transcription activator activity, RNA polymerase II-specific of NF-Y,SREBP1A,1C,2 [nucleoplasm]

Class:IdCatalystActivity:9987240
_displayNameDNA-binding transcription activator activity, RNA polymerase II-specific of NF-Y,SREBP1A,1C,2 [nucleoplasm]
_timestamp2026-04-10 21:51:23
activity[GO_MolecularFunction:2266140] DNA-binding transcription activator activity, RNA polymerase II-specific
created[InstanceEdit:9987236] D'Eustachio, Peter, 2026-04-10
modified[InstanceEdit:9987261] D'Eustachio, Peter, 2026-04-10
physicalEntity[Complex:1655728] SREBP1A,1C,2:NF-Y [nucleoplasm] [Homo sapiens]
(catalystActivity)[Reaction:2065966] SREBP1A,1C,2 binds the TM7SF2 promoter [Homo sapiens]
[Reaction:2426147] SREBP1A,1C,2 binds the FDPS promoter [Homo sapiens]
[Reaction:2426150] SREBP1A,1C,2 binds the HMGCS1 promoter [Homo sapiens]
[CatalystActivityReference:9987319] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y [nucleoplasm] Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase
[CatalystActivityReference:9987320] DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C,2,NF-Y [nucleoplasm] Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells
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No pathways have been reviewed or authored by DNA-binding transcription activator activity, RNA polymerase II-specific of NF-Y,SREBP1A,1C,2 [nucleoplasm] (9987240)
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