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Details on Person SEC61 translocon:TRAP:nascent membrane polypeptide binds OST complex

Class:Id	Reaction:9987039
_displayName	SEC61 translocon:TRAP:nascent membrane polypeptide binds OST complex
_timestamp	2026-05-04 18:13:48
authored	[InstanceEdit:9987034] May, Bruce, 2026-04-08
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9987008] May, Bruce, 2026-04-09
edited	[InstanceEdit:9987034] May, Bruce, 2026-04-08
input	[Complex:9986696] SEC61 translocon:TRAP:nascent membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens] [DefinedSet:532516] OST complex [endoplasmic reticulum membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9987018] Structural basis of regulated N-glycosylation at the secretory translocon [LiteratureReference:9986948] Visualization of translation and protein biogenesis at the ER membrane [LiteratureReference:9987016] Global analysis of translocon remodeling during protein synthesis at the ER [LiteratureReference:9986708] Substrate-driven assembly of a translocon for multipass membrane proteins [LiteratureReference:9987143] Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon
modified	[InstanceEdit:9987127] May, Bruce, 2026-04-09 [InstanceEdit:9987160] May, Bruce, 2026-04-10 [InstanceEdit:9988168] May, Bruce, 2026-05-04
name	SEC61 translocon:TRAP:nascent membrane polypeptide binds OST complex
output	[Complex:9987021] SEC61 translocon:TRAP:OST:nascent membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:9986704] SRP:SRP receptor transfers nascent membrane polypeptide to SEC61 translocon:TRAP complex [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9987044] R-HSA-9987039.1
summation	[Summation:9987033] The OST glycosyltransferase complex is cotranslationally rec...
(hasEvent)	[Pathway:9986646] Cotranslational targeting of proteins to the endoplasmic reticulum [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9987037] SEC61 translocon:TRAP:OST inserts protein into endoplasmic reticulum membrane [Homo sapiens]
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No pathways have been reviewed or authored by SEC61 translocon:TRAP:nascent membrane polypeptide binds OST complex (9987039)