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Details on Person Mechanism of signal-anchor triage during early steps of membrane protein insertion

Class:IdLiteratureReference:9986829
_displayNameMechanism of signal-anchor triage during early steps of membrane protein insertion
_timestamp2026-04-06 16:08:12
author[Person:9986846] Wu, Haoxi
[Person:5250556] Hegde, Ramanujan S
created[InstanceEdit:9986840] May, Bruce, 2026-04-06
journalMol Cell
pages961-973.e7
pubMedIdentifier36764302
titleMechanism of signal-anchor triage during early steps of membrane protein insertion
volume83
year2023
(literatureReference)[Pathway:9986646] Cotranslational targeting of proteins to the endoplasmic reticulum [Homo sapiens]
[Reaction:9986695] SRP:GTP:SRP receptor:GTP transfers nascent membrane polypeptide to endoplasmic reticulum membrane complex (EMC) [Homo sapiens]
[Reaction:9986704] SRP:SRP receptor transfers nascent membrane polypeptide to SEC61 translocon:TRAP complex [Homo sapiens]
[BlackBoxEvent:9986721] Endoplasmic reticulum membrane complex (EMC) inserts protein into endoplasmic reticulum membrane [Homo sapiens]
[Reaction:9988089] SRP:GTP:SRP receptor:GTP transfers nascent polypeptide containing signal peptide or signal anchor to SEC61 translocon:TRAP complex [Homo sapiens]
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