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Details on Person Substrate-driven assembly of a translocon for multipass membrane proteins
| Class:Id | LiteratureReference:9986708 |
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| _displayName | Substrate-driven assembly of a translocon for multipass membrane proteins |
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| _timestamp | 2026-04-04 15:22:28 |
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| author | [Person:9986698] Sundaram, Arunkumar
[Person:9986710] Yamsek, Melvin
[Person:9986709] Zhong, Frank
[Person:9986697] Hooda, Yogesh
[Person:5250556] Hegde, Ramanujan S
[Person:9610470] Keenan, Robert J |
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| created | [InstanceEdit:9986705] May, Bruce, 2026-04-04 |
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| journal | Nature |
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| pages | 167-172 |
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| pubMedIdentifier | 36261522 |
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| title | Substrate-driven assembly of a translocon for multipass membrane proteins |
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| volume | 611 |
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| year | 2022 |
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| (literatureReference) | [Pathway:9986646] Cotranslational targeting of proteins to the endoplasmic reticulum [Homo sapiens]
[Reaction:9986702] SEC61 translocon:TRAP:nascent membrane polypeptide binds BOS, PAT, and GEL complexes yielding the multipass transmembrane translocon (MPT) [Homo sapiens]
[BlackBoxEvent:9986731] Multipass translocon (MPT) inserts protein into endoplasmic reticulum membrane [Homo sapiens]
[Reaction:9987039] SEC61 translocon:TRAP:nascent membrane polypeptide binds OST complex [Homo sapiens]
[Complex:9986700] Translocon:TRAP:MPT:nascent multipass ER membrane polypeptide:80S ribosome:mRNA [endoplasmic reticulum membrane] [Homo sapiens]
[DefinedSet:9986725] protein inserted by Translocon:TRAP:MPT [endoplasmic reticulum membrane] [Homo sapiens] |
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