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Details on Person POLRMT binds TFAM:mitochondrial promoter

Class:Id	Reaction:9986307
_displayName	POLRMT binds TFAM:mitochondrial promoter
_timestamp	2026-03-31 19:44:54
authored	[InstanceEdit:9986239] May, Bruce, 2026-03-27
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9986303] May, Bruce, 2026-03-29
edited	[InstanceEdit:9986239] May, Bruce, 2026-03-27
input	[Complex:163298] TFAM:mitochondrial promoter complex [mitochondrial matrix] [Homo sapiens] [EntityWithAccessionedSequence:163267] POLRMT [mitochondrial matrix] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9986237] A novel intermediate in transcription initiation by human mitochondrial RNA polymerase [LiteratureReference:9986236] Organization of the human mitochondrial transcription initiation complex [LiteratureReference:9986231] A model for transcription initiation in human mitochondria [LiteratureReference:9986308] Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription [LiteratureReference:9985720] Structural Basis of Mitochondrial Transcription Initiation
modified	[InstanceEdit:9986398] May, Bruce, 2026-03-31
name	POLRMT binds TFAM:mitochondrial promoter
output	[Complex:9986300] POLRMT:TFAM:mitochondrial promoter [mitochondrial matrix] [Homo sapiens]
precedingEvent	[Reaction:163310] TFAM binds to mitochondrial promoters [Homo sapiens] [BlackBoxEvent:1592229] TFAM translocates from the cytosol to the mitochondrial matrix [Homo sapiens] [BlackBoxEvent:1592243] Expression of POLRMT [Homo sapiens] [Reaction:1592240] Formation of NRF2 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9986310] R-HSA-9986307.1
summation	[Summation:9986304] POLRMT binds TFAM at the mitochondrial promoter (Yakubovskay...
(hasEvent)	[Pathway:9985686] Mitochondrial transcription [Homo sapiens]
(precedingEvent)	[Reaction:9986213] TFB2M binds POLRMT:TFAM:mitochondrial promoter complex [Homo sapiens]
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No pathways have been reviewed or authored by POLRMT binds TFAM:mitochondrial promoter (9986307)