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Details on Person Enzyme assays for synthesis and degradation of 2-5As and other 2'-5' oligonucleotides

Class:IdLiteratureReference:9985938
_displayNameEnzyme assays for synthesis and degradation of 2-5As and other 2'-5' oligonucleotides
_timestamp2026-03-26 20:44:46
author[Person:9614515] Poulsen, Jesper Buchhave
[Person:9614509] Kjær, Karina Hansen
[Person:380237] Justesen, J
[Person:9614532] Martensen, Pia Møller
created[InstanceEdit:9985788] Shamovsky, Veronica, 2026-03-26
journalBMC Biochem
pages15
pubMedIdentifier26113370
titleEnzyme assays for synthesis and degradation of 2-5As and other 2'-5' oligonucleotides
volume16
year2015
(literatureReference)[Polymerisation:8983680] OAS1 produces oligoadenylates [Homo sapiens]
[Reaction:9985802] SARS-CoV-2 dsRNA-bound GGC-OAS1 produces 2'-5' oligoadenylates [Homo sapiens]
[Summation:8983710] In the cytosol, human 2′-5′-oligoadenylate synthetase 1 (OAS...
[Summation:9012240] When bound to viral double-stranded RNA (dsRNA), cytosolic 2...
[Summation:9985825] During severe acute respiratory syndrome coronavirus 2 (SARS...
[Summation:9985837] When bound to viral double-stranded RNA (dsRNA), 2′-5′-oligo...
[Summation:9985884] During infection, particularly with positive-sense RNA virus...
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