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Details on Person The mitochondrial RNA polymerase POLRMT in a complex with TF...
| Class:Id | Summation:9985772 |
|---|---|
| _displayName | The mitochondrial RNA polymerase POLRMT in a complex with TF... |
| _timestamp | 2026-04-22 21:48:24 |
| created | [InstanceEdit:9985770] May, Bruce, 2026-03-26 |
| modified | [InstanceEdit:9986311] May, Bruce, 2026-03-29 [InstanceEdit:9987659] May, Bruce, 2026-04-22 |
| text | The mitochondrial RNA polymerase POLRMT in a complex with TFB2M and mitochondrial DNA further extends the 5 nucleotide RNA to 8-9 nucleotides (based on cryo-EM structures of transcription intermediates in Herbine et al. 2025). The extended RNA clashes with the initiation factor TFB2M, causing TFB2M to dissociate (Herbine et al. 2025). |
| (summation) | [Reaction:9985666] POLRMT in POLRMT:TFB2M:mitochondrial promoter:5 nt RNA extends 5 nt RNA to 8-9 nt and TFB2M dissociates from POLRMT:TFB2M:mitochondrial DNA [Homo sapiens] |
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No pathways have been reviewed or authored by The mitochondrial RNA polymerase POLRMT in a complex with TF... (9985772)
