Query author contributions in Reactome
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Details on Person AMPK activated by the agonist metformin phosphorylates serin...
| Class:Id | Summation:9984186 |
|---|---|
| _displayName | AMPK activated by the agonist metformin phosphorylates serin... |
| _timestamp | 2026-03-04 20:56:42 |
| created | [InstanceEdit:9984181] May, Bruce, 2026-03-04 |
| text | AMPK activated by the agonist metformin phosphorylates serine-389 of CSNK1E (CKIepsilon), resulting in increased phosphorylation of PER2 by CSNK1E, which enhances the degradation of PER2 (inferred from mouse homologs in Um et al. 2007). The overall effect of metformin on the circadian cycle is to increase the amplitude and decrease the period (inferred from mice in Um et al. 2007). |
| (summation) | [Reaction:9859709] AMPK phosphorylates CKIepsilon [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by AMPK activated by the agonist metformin phosphorylates serin... (9984186)
