Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person LANA1 recruits the PRC2 complex

Class:Id	Reaction:9983755
_displayName	LANA1 recruits the PRC2 complex
_doRelease	FALSE
_timestamp	2026-03-23 08:55:17
authored	[InstanceEdit:9983746] Stephan, Ralf, 2026-02-27
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9983764] Stephan, Ralf, 2026-02-27
disease	[Disease:3134794] viral infectious disease
input	[Complex:9981981] Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] [Homo sapiens] [Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9983762] Epigenetic analysis of KSHV latent and lytic genomes [LiteratureReference:9983767] Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection [LiteratureReference:9983390] LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection [LiteratureReference:9983759] ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation [LiteratureReference:9983756] Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency [LiteratureReference:9983757] Epigenetic and epitranscriptomic regulation during oncogenic γ-herpesvirus infection
modified	[InstanceEdit:9985631] Stephan, Ralf, 2026-03-23
name	LANA1 recruits the PRC2 complex
output	[Complex:9983760] PRC2 complex:Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9973876] LANA1 tethers HHV8 circular dsDNA to host chromosomes [Homo sapiens] [BlackBoxEvent:9973875] HHV8 dsDNA circularizes into an episome [Homo sapiens] [Reaction:9980758] LANA1 oligomerizes on episome [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9983774] R-HSA-9983755.1
summation	[Summation:9983765] The core Polycomb Repressive Complex 2 (PRC2) interacts with...
(hasEvent)	[Pathway:9983305] Establishment of Latent HHV8 Infection [Homo sapiens]
(precedingEvent)	[Reaction:9983784] PRC2 complex methylates histone H3 on ORF50 promoter [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by LANA1 recruits the PRC2 complex (9983755)