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Details on Person The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress

Class:IdLiteratureReference:9982337
_displayNameThe NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress
_timestamp2026-02-17 02:28:57
author[Person:9982354] Zu, Yumeng
[Person:9982336] Wu, Chou
[Person:9982339] Li, Feifei
[Person:2744280] Yao, Hong
[Person:9982325] Xia, Yuyue
[Person:9982360] Zhang, Ruoxi
[Person:9982348] Li, Lulu
[Person:9982332] Chen, Shuangquan
[Person:9982334] Shi, Qi
[Person:9982361] Xi, Shuang
[Person:9982362] Pang, Huanhuan
[Person:9925241] Liu, Minghui
[Person:9982330] Wang, Leibo
[Person:9982338] Terpack, Sandi
[Person:9982322] Wang, Weihua
[Person:5218910] Chen, She
[Person:5318815] Zhang, Hong
[Person:9982363] Wang, Yibing
[Person:9749262] Yang, Maojun
[Person:9916268] Huang, Shanjin
[Person:9982345] Zhou, Fuling
[Person:9982353] Tang, Yu
[Person:9795435] Hu, Zeping
[Person:2682291] Fan, Shilong
[Person:9982358] Tang, Yefeng
[Person:5653639] Lee, Young-Sam
[Person:9982341] Wang, Gelin
created[InstanceEdit:9982344] May, Bruce, 2026-02-17
journalMol Cell
pages2271-2286.e6
pubMedIdentifier40505662
titleThe NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress
volume85
year2025
(literatureReference)[RegulationReference:9984532] Negative regulation by 'adenosine 5'-monophosphate [cytosol]' The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress
[Reaction:9961787] NAMPT transfers 5-phosphoribose from 5-phosphoribosyl-1-pyrophosphate (PRPP) to nicotinamide (NAM) , yielding nicotinamide mononucleotide (NMN) and pyrophosphate (PPi) [Homo sapiens]
[Reaction:9961800] NAMPT transfers 5-phosphoribose from 5-phosphoribose-1-pyrophosphate (PRPP) to nicotinamide (NAM), yielding nicotinamide mononucleotide (NMN) and pyrophosphate [Homo sapiens]
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