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Details on Person ORF50:DNA recruits the replication complex

Class:Id	Reaction:9982118
_displayName	ORF50:DNA recruits the replication complex
_doRelease	FALSE
_timestamp	2026-06-04 17:17:24
authored	[InstanceEdit:9982101] Stephan, Ralf, 2026-02-13
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9982115] Stephan, Ralf, 2026-02-13
disease	[Disease:3134794] viral infectious disease
input	[Complex:9982104] HHV8 Circular Episome:ORF50 [nucleoplasm] [Human herpesvirus 8] [Complex:9982132] p-Replication complex [nucleoplasm] [Human herpesvirus 8]
isChimeric	FALSE
literatureReference	[LiteratureReference:9982116] Interaction of Kaposi's sarcoma-associated herpesvirus ORF59 with oriLyt is dependent on binding with K-Rta [LiteratureReference:9979037] Phosphorylation of Kaposi's sarcoma-associated herpesvirus processivity factor ORF59 by a viral kinase modulates its ability to associate with RTA and oriLyt
modified	[InstanceEdit:9982131] Stephan, Ralf, 2026-02-14 [InstanceEdit:9983303] Stephan, Ralf, 2026-02-21 [InstanceEdit:9991267] Stephan, Ralf, 2026-06-04
name	ORF50:DNA recruits the replication complex
output	[Complex:9982117] Episome:ORF50:RC [nucleoplasm] [Human herpesvirus 8]
precedingEvent	[Reaction:9982118] ORF50:DNA recruits the replication complex [Homo sapiens] [BlackBoxEvent:9981203] Replication complex moves to nucleus [Homo sapiens] [Reaction:9981630] Replisome and helicase-primase subcomplexes form replication complex [Homo sapiens] [Reaction:9982105] ORF50 binds the circular episome [Homo sapiens] [BlackBoxEvent:9973875] HHV8 dsDNA circularizes into an episome [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9982119] R-HSA-9982118.1
structureModified	[InstanceEdit:9982131] Stephan, Ralf, 2026-02-14
summation	[Summation:9982113] HHV8 DNA polymerase processivity factor (ORF59, PF-8) subuni...
(hasEvent)	[Pathway:9987685] HHV8 Lytic Genome Replication [Homo sapiens]
(precedingEvent)	[Reaction:9982118] ORF50:DNA recruits the replication complex [Homo sapiens]
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No pathways have been reviewed or authored by ORF50:DNA recruits the replication complex (9982118)