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Details on Person Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm]

Class:Id	Complex:9981981
_displayName	Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm]
_timestamp	2026-02-24 14:40:24
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9981984] Orlic-Milacic, Marija, 2026-02-12
disease	[Disease:3134794] viral infectious disease
hasComponent	[Complex:9982061] Condensed prophase chromosome [nucleoplasm] [Homo sapiens] [DefinedSet:9982043] Chromosome DNA [nucleoplasm] [Homo sapiens] [Complex:181921] Nucleosome [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181914] HIST3H3 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181914] HIST3H3 [nucleoplasm] [Homo sapiens] [Complex:9983417] HHV8 Circular Episome:Me-R20-p-S10,T14-LANA1 oligomer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9979916] HHV8 Circular Episome [nucleoplasm] [Human herpesvirus 8] [Complex:9980759] Me-R20-p-S10,T14-LANA1 oligomer [nucleoplasm] [Human herpesvirus 8] [Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978627] Me-R20-p-S10,T14-LANA1 [nucleoplasm] [Human herpesvirus 8]
isChimeric	FALSE
modified	[InstanceEdit:9982097] Orlic-Milacic, Marija, 2026-02-13 [InstanceEdit:9983392] Stephan, Ralf, 2026-02-23 [InstanceEdit:9983419] Orlic-Milacic, Marija, 2026-02-24
name	Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome
relatedSpecies	[Species:2671781] Human herpesvirus 8
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9981992] R-HSA-9981981.1
(hasComponent)	[Complex:9983394] SIRT1:Tethered HHV8 Genome [nucleoplasm] [Homo sapiens] [Complex:9983695] SET1A complex:Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] [Homo sapiens] [Complex:9983760] PRC2 complex:Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9983687] LANA1 recruits the SET1A complex [Homo sapiens] [Reaction:9983755] LANA1 recruits the PRC2 complex [Homo sapiens] [Reaction:9985150] PAN RNA binds to LANA1 [Homo sapiens] [Reaction:9985155] LANA1 dissociates from episome [Homo sapiens]
(output)	[Reaction:9973876] LANA1 tethers HHV8 circular dsDNA to host chromosomes [Homo sapiens] [Reaction:9984378] Dissociation of PRC2 from episome [Homo sapiens]
(regulator)	[PositiveRegulation:9984493] Positive regulation by 'Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm]'
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No pathways have been reviewed or authored by Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] (9981981)