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Details on Person RSAD2 dimer oxidizes L-Met in HELI

Class:Id	BlackBoxEvent:9981426
_displayName	RSAD2 dimer oxidizes L-Met in HELI
_doRelease	FALSE
_timestamp	2026-03-26 19:14:34
authored	[InstanceEdit:9981409] Stephan, Ralf, 2026-02-09
catalystActivity	[CatalystActivity:9981418] oxidoreductase activity, acting on a sulfur group of donors of RSAD2 dimer:4Fe-4S [lipid droplet]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9981424] Stephan, Ralf, 2026-02-09
disease	[Disease:3134794] viral infectious disease
goBiologicalProcess	[GO_BiologicalProcess:258214] post-translational protein modification
input	[EntityWithAccessionedSequence:9981410] OGlcNAc-HELI [cytosol] [Human herpesvirus 8] [SimpleEntity:71284] AdoMet [cytosol]
internalReviewed	[InstanceEdit:9985769] Orlic-Milacic, Marija, 2026-03-26
isChimeric	FALSE
literatureReference	[LiteratureReference:9981427] Viperin catalyzes methionine oxidation to promote protein expression and function of helicases
modified	[InstanceEdit:9981620] Stephan, Ralf, 2026-02-10 [InstanceEdit:9983303] Stephan, Ralf, 2026-02-21 [InstanceEdit:9985311] Stephan, Ralf, 2026-03-18 [InstanceEdit:9985778] Stephan, Ralf, 2026-03-26
name	RSAD2 dimer oxidizes L-Met in HELI
output	[EntityWithAccessionedSequence:9981416] MetO-M401,OGlcNAc-HELI [cytosol] [Human herpesvirus 8] [SimpleEntity:1130791] 5'-deoxyadenosine [cytoplasm] [SimpleEntity:174390] L-Met [cytosol]
precedingEvent	[Reaction:9981407] OGT O-glycosylates HELI [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9981429] R-HSA-9981426.1
summation	[Summation:9981415] S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 ...
(hasEvent)	[Pathway:9976070] Maturation/Activation of Late HHV8 Lytic Proteins [Homo sapiens]
(precedingEvent)	[Reaction:9981623] HELI, ORF56, ORF40:DBP form the helicase-primase subcomplex [Homo sapiens]
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No pathways have been reviewed or authored by RSAD2 dimer oxidizes L-Met in HELI (9981426)