Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Name Email address

Details on Person UniProt:Q8WXF3 RLN3

Class:IdReferenceGeneProduct:99811
_chainChangeLogsignal peptide:1-25 added on Fri February 6 2015;peptide:26-52 added on Fri February 6 2015;propeptide:55-118 added on Fri February 6 2015;peptide:119-142 added on Fri February 6 2015
_displayNameUniProt:Q8WXF3 RLN3
_timestamp2023-11-03 16:45:51
chainsignal peptide:1-25
peptide:26-52
propeptide:55-118
peptide:119-142
checksum23A3E095034B31E4
commentFUNCTION May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.SUBUNIT Heterodimer of a B chain and an A chain linked by two disulfide bonds.INTERACTION Belongs to the insulin family.
descriptionrecommendedName: Relaxin-3 alternativeName: Insulin-like peptide INSL7 shortName: Insulin-like peptide 7 alternativeName: Prorelaxin H3 component recommendedName: Relaxin-3 B chain /component component recommendedName: Relaxin-3 A chain /component
geneNameRLN3
INSL7
RXN3
ZINS4
UNQ6188/PRO20213
identifierQ8WXF3
isSequenceChangedFALSE
keyword3D-structure
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Hormone
Reference proteome
Secreted
Signal
modified[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:8987656] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9688885] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameRLN3
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9003766] ENSEMBL:ENSG00000171136 RLN3 [Homo sapiens]
secondaryIdentifierREL3_HUMAN
Q6UXW5
sequenceLength142
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:444820] RLN3(119-142) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:444849] RLN3(26-52) [extracellular region] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q8WXF3 RLN3 (99811)