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Details on Person JAG1 (stalk cell) binds Fringe-modified NOTCH1 (tip cell)

Class:IdReaction:9980904
_displayNameJAG1 (stalk cell) binds Fringe-modified NOTCH1 (tip cell)
_timestamp2026-03-18 16:42:38
authored[InstanceEdit:9980952] May, Bruce, 2026-01-31
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9980923] May, Bruce, 2026-02-04
edited[InstanceEdit:9980952] May, Bruce, 2026-01-31
input[EntityWithAccessionedSequence:157098] JAG1 [plasma membrane] [Homo sapiens]
[Complex:1911516] Fringe-modified NOTCH1 [plasma membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9985318] D'Eustachio, Peter, 2026-03-18
isChimericFALSE
literatureReference[LiteratureReference:2050621] The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
modified[InstanceEdit:9981121] May, Bruce, 2026-02-05
[InstanceEdit:9981222] May, Bruce, 2026-02-06
[InstanceEdit:9981978] May, Bruce, 2026-02-12
[InstanceEdit:9985321] May, Bruce, 2026-03-18
nameJAG1 (stalk cell) binds Fringe-modified NOTCH1 (tip cell)
output[Complex:9980907] JAG1:Fringe-modified NOTCH1 [plasma membrane] [Homo sapiens]
participantCellType[PhysicalEntityCellType:9980911] JAG1 [plasma membrane] in endothelial stalk cell
[PhysicalEntityCellType:9981111] Fringe-modified NOTCH1 [plasma membrane] in endothelial tip cell
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9980979] R-HSA-9980904.1
summation[Summation:9981221] At the leading front of an angiogenic sprout in mice, stalk ...
(hasEvent)[Pathway:9917416] Sprouting angiogenesis [Homo sapiens]
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No pathways have been reviewed or authored by JAG1 (stalk cell) binds Fringe-modified NOTCH1 (tip cell) (9980904)
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