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Details on Person ORF9 and ORF59 form the replisome subcomplex

Class:Id	Reaction:9980730
_displayName	ORF9 and ORF59 form the replisome subcomplex
_doRelease	FALSE
_timestamp	2026-03-26 19:14:25
authored	[InstanceEdit:9980714] Stephan, Ralf, 2026-02-02
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9980729] Stephan, Ralf, 2026-02-02
disease	[Disease:3134794] viral infectious disease
input	[EntityWithAccessionedSequence:9979739] ORF9 [cytosol] [Human herpesvirus 8] [Complex:9978984] ORF59 dimer [cytosol] [Human herpesvirus 8]
internalReviewed	[InstanceEdit:9985769] Orlic-Milacic, Marija, 2026-03-26
isChimeric	FALSE
literatureReference	[LiteratureReference:9979025] Processivity factor of KSHV contains a nuclear localization signal and binding domains for transporting viral DNA polymerase into the nucleus [LiteratureReference:9980715] Interaction and assembly of the DNA replication core proteins of Kaposi's sarcoma-associated herpesvirus
modified	[InstanceEdit:9981308] Stephan, Ralf, 2026-02-07 [InstanceEdit:9983303] Stephan, Ralf, 2026-02-21 [InstanceEdit:9985311] Stephan, Ralf, 2026-03-18 [InstanceEdit:9985778] Stephan, Ralf, 2026-03-26
name	ORF9 and ORF59 form the replisome subcomplex
output	[Complex:9980732] Replisome subcomplex [cytosol] [Human herpesvirus 8]
precedingEvent	[Reaction:9978985] ORF59 forms dimer [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9980734] R-HSA-9980730.1
summation	[Summation:9980731] DNA polymerase catalytic subunit ORF9 (Pol-8) binds to HHV8 ...
(hasEvent)	[Pathway:9976070] Maturation/Activation of Late HHV8 Lytic Proteins [Homo sapiens]
(precedingEvent)	[Reaction:9981630] Replisome and helicase-primase subcomplexes form replication complex [Homo sapiens]
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No pathways have been reviewed or authored by ORF9 and ORF59 form the replisome subcomplex (9980730)