Query author contributions in Reactome
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Details on Person HHV8 Protein K4 (vMIP-II) is a viral CC chemokine homolog. I...
| Class:Id | Summation:9980500 |
|---|---|
| _displayName | HHV8 Protein K4 (vMIP-II) is a viral CC chemokine homolog. I... |
| _timestamp | 2026-01-29 10:21:28 |
| created | [InstanceEdit:9980515] Stephan, Ralf, 2026-01-29 |
| text | HHV8 Protein K4 (vMIP-II) is a viral CC chemokine homolog. It binds to the viral G-protein coupled receptor (ORF74), inhibiting its signaling (Geras-Raaka et al., 1998; Palande et al., 2025; Kleist et al., 2025). Inhibition of ORF74 promotes cell survival and limits ORF74-driven tumorigenesis (autocrine activity). It also might foster immune evasion during specific phases of KSHV infection (reviewed in Couty & Gershengorn, 2004; Szpakowska & Chevigné, 2016; Pontejo et al., 2018). |
| (summation) | [Reaction:9980517] K4 binds to ORF74 [Homo sapiens] |
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No pathways have been reviewed or authored by HHV8 Protein K4 (vMIP-II) is a viral CC chemokine homolog. I... (9980500)
