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Query author contributions in Reactome

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Details on Person mTORC2:PIP3 [plasma membrane]

Class:IdComplex:9980228
_displayNamemTORC2:PIP3 [plasma membrane]
_timestamp2026-02-09 14:20:02
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9980227] Orlic-Milacic, Marija, 2026-01-26
hasComponent
literatureReference[LiteratureReference:6795320] Identification of Protor as a novel Rictor-binding component of mTOR complex-2
[LiteratureReference:6795293] PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling
modified[InstanceEdit:9980269] Orlic-Milacic, Marija, 2026-01-26
[InstanceEdit:9981438] Orlic-Milacic, Marija, 2026-02-09
namemTORC2:PIP3
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9980235] R-HSA-9980228.1
(activeUnit)[CatalystActivity:9981469] protein serine/threonine kinase activity of p-T566-PRKCE:mTORC2:PIP3 [plasma membrane]
(hasComponent)[Complex:9980260] NICD1:mTORC2:PIP3 [plasma membrane] [Homo sapiens]
[Complex:9981461] p-T566-PRKCE:mTORC2:PIP3 [plasma membrane] [Homo sapiens]
[Complex:9981472] p-T566,T710-PRKCE:mTORC2:PIP3 [cytosol] [Homo sapiens]
[Complex:9981484] p-T566,T710,S729-PRKCE:mTORC2:PIP3 [plasma membrane] [Homo sapiens]
(input)[BlackBoxEvent:9980257] NICD1 binds mTORC2 [Homo sapiens]
[Reaction:9981456] PRKCE binds mTORC2 [Homo sapiens]
(output)[Reaction:9980233] PIP3 activates mTORC2 [Homo sapiens]
[Reaction:9981494] Activated PRKCE dissociates from mTORC2 [Homo sapiens]
(physicalEntity)[CatalystActivity:198624] protein serine/threonine kinase activity of mTORC2:PIP3 [plasma membrane]
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No pathways have been reviewed or authored by mTORC2:PIP3 [plasma membrane] (9980228)