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Details on Person PRMT1 methylates Arg-20 in LANA1 dimer

Class:IdBlackBoxEvent:9978628
_displayNamePRMT1 methylates Arg-20 in LANA1 dimer
_doReleaseFALSE
_timestamp2026-03-26 18:30:35
authored[InstanceEdit:9978570] Stephan, Ralf, 2026-01-02
catalystActivity[CatalystActivity:9978629] protein-arginine N-methyltransferase activity of PRMT1 dimer [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9978626] Stephan, Ralf, 2026-01-03
disease[Disease:3134794] viral infectious disease
goBiologicalProcess[GO_BiologicalProcess:160602] peptidyl-arginine omega-N-methylation
input[SimpleEntity:77087] AdoMet [nucleoplasm]
[SimpleEntity:77087] AdoMet [nucleoplasm]
[Complex:9979213] p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8]
internalReviewed[InstanceEdit:9985769] Orlic-Milacic, Marija, 2026-03-26
isChimericFALSE
literatureReference[LiteratureReference:9976831] Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV
[LiteratureReference:9978630] Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen
modified[InstanceEdit:9978665] Stephan, Ralf, 2026-01-04
[InstanceEdit:9978727] Stephan, Ralf, 2026-01-05
[InstanceEdit:9979224] Stephan, Ralf, 2026-01-16
[InstanceEdit:9983303] Stephan, Ralf, 2026-02-21
[InstanceEdit:9983420] Orlic-Milacic, Marija, 2026-02-24
[InstanceEdit:9985748] Stephan, Ralf, 2026-03-25
[InstanceEdit:9985768] Stephan, Ralf, 2026-03-26
namePRMT1 methylates Arg-20 in LANA1 dimer
output[SimpleEntity:9668967] H+ [nucleoplasm]
[SimpleEntity:9668967] H+ [nucleoplasm]
[Complex:9978636] Me-R20-p-S10,T14-LANA1 dimer [nucleoplasm] [Human herpesvirus 8]
[SimpleEntity:77502] AdoHcy [nucleoplasm]
[SimpleEntity:77502] AdoHcy [nucleoplasm]
precedingEvent
relatedSpecies[Species:2671781] Human herpesvirus 8
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9978638] R-HSA-9978628.1
structureModified[InstanceEdit:9979224] Stephan, Ralf, 2026-01-16
summation[Summation:9978632] Host Protein arginine N-methyltransferase 1 (PRMT1) monometh...
(hasEvent)[Pathway:9976043] Maturation of Latency-Associated HHV8 Proteins [Homo sapiens]
(precedingEvent)[Reaction:9978650] LANA1 binds ORF50 tetramer [Homo sapiens]
[Reaction:9980757] LANA1 binds LANA promoter [Homo sapiens]
[Reaction:9980758] LANA1 oligomerizes on episome [Homo sapiens]
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No pathways have been reviewed or authored by PRMT1 methylates Arg-20 in LANA1 dimer (9978628)