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Details on Person Gata3 binds the Il5 gene

Class:IdReaction:9978124
_displayNameGata3 binds the Il5 gene
_doReleaseTRUE
_timestamp2026-02-26 19:18:44
authored[InstanceEdit:9978120] May, Bruce, 2025-12-27
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9978109] May, Bruce, 2025-12-27
edited[InstanceEdit:9978120] May, Bruce, 2025-12-27
input[EntityWithAccessionedSequence:9830515] Gata3 [nucleoplasm] [Mus musculus]
[EntityWithAccessionedSequence:9830515] Gata3 [nucleoplasm] [Mus musculus]
[EntityWithAccessionedSequence:9830515] Gata3 [nucleoplasm] [Mus musculus]
[EntityWithAccessionedSequence:9978126] Il5 gene [nucleoplasm] [Mus musculus]
internalReviewed[InstanceEdit:9978792] Matthews, Lisa, 2026-01-07
isChimericFALSE
literatureReference[LiteratureReference:9976372] Characterization of cis-regulatory elements and nuclear factors conferring Th2-specific expression of the IL-5 gene: a role for a GATA-binding protein
[LiteratureReference:9976122] Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity
[LiteratureReference:9977453] Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements
[LiteratureReference:9977460] Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
[LiteratureReference:9977771] Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
[LiteratureReference:9977772] Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
modified[InstanceEdit:9979435] May, Bruce, 2026-01-19
[InstanceEdit:9983437] May, Bruce, 2026-02-24
[InstanceEdit:9983731] May, Bruce, 2026-02-26
nameGata3 binds the Il5 gene
output[Complex:9978096] Gata3:Il5 gene [nucleoplasm] [Mus musculus]
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2026-03-25
reviewed[InstanceEdit:9983436] Barbutti, Isabella, 2026-02-24
[InstanceEdit:9983730] Lord, Graham M, 2026-02-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9978133] R-MMU-9978124.1
summation[Summation:9978107] Gata3 binds 3 sites in the proximal 400 bp of the Il5 promot...
(inferredFrom)[Reaction:9976390] GATA3 binds the IL5 gene [Homo sapiens]
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