Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3

Class:Id	BlackBoxEvent:9977991
_displayName	Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3
_doRelease	TRUE
_timestamp	2026-02-26 19:19:42
authored	[InstanceEdit:9978005] May, Bruce, 2025-12-24
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9978007] May, Bruce, 2025-12-27
edited	[InstanceEdit:9978005] May, Bruce, 2025-12-24
input	[EntityWithAccessionedSequence:9830509] Gata3 gene [nucleoplasm] [Mus musculus]
internalReviewed	[InstanceEdit:9978792] Matthews, Lisa, 2026-01-07
isChimeric	FALSE
literatureReference	[LiteratureReference:9976105] STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells [LiteratureReference:9942710] Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation [LiteratureReference:9976107] Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor [LiteratureReference:9977600] Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch [LiteratureReference:9977594] Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells [LiteratureReference:9977768] Notch directly regulates Gata3 expression during T helper 2 cell differentiation
modified	[InstanceEdit:9979435] May, Bruce, 2026-01-19 [InstanceEdit:9983437] May, Bruce, 2026-02-24 [InstanceEdit:9983731] May, Bruce, 2026-02-26
name	Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3
output	[EntityWithAccessionedSequence:9830515] Gata3 [nucleoplasm] [Mus musculus]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9977995] Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]'
regulationReference	[RegulationReference:9977971] Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]' STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
releaseDate	2026-03-25
reviewed	[InstanceEdit:9983436] Barbutti, Isabella, 2026-02-24 [InstanceEdit:9983730] Lord, Graham M, 2026-02-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9978048] R-MMU-9977991.1
summation	[Summation:9978006] Phosphorylated Stat6 dimers resulting from Il4 signaling and...
(inferredFrom)	[BlackBoxEvent:9976143] STAT6, NFATC2 (NFAT1), and NICD1,2 positively regulate expression of GATA3 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3 (9977991)