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Details on Person An unknown kinase phosphorylates HHV8 Post-transcriptional r...

Class:IdSummation:9977871
_displayNameAn unknown kinase phosphorylates HHV8 Post-transcriptional r...
_timestamp2026-03-22 08:59:56
created[InstanceEdit:9977859] Stephan, Ralf, 2025-12-24
modified[InstanceEdit:9977879] Stephan, Ralf, 2025-12-24
[InstanceEdit:9985626] Stephan, Ralf, 2026-03-22
textAn unknown kinase phosphorylates HHV8 Post-transcriptional regulator MTA (ORF57) on Ser-95 and Ser-97. It has been shown that the casein kinase 2 complex (CK2, CKII) can act as the required kinase in vitro but the actual kinase acting in vivo is unknown. Phosphorylation prevents degradation of ORF57. These findings were established using recombinant proteins and experiments in human (HEK293, HeLa, JSC-1, BCBL-1) and monkey (COS-1) cell lines (Majerciak et al., 2015).
(summation)[Reaction:9977862] Unknown kinase phosphorylates ORF57 [Homo sapiens]
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