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Details on Person Unknown kinase phosphorylates ORF57

Class:Id	Reaction:9977862
_displayName	Unknown kinase phosphorylates ORF57
_doRelease	FALSE
_timestamp	2026-03-26 18:48:43
authored	[InstanceEdit:9977815] Stephan, Ralf, 2025-12-23
catalystActivity	[CatalystActivity:9767993] protein serine/threonine kinase activity of unknown kinase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9977859] Stephan, Ralf, 2025-12-24
disease	[Disease:3134794] viral infectious disease
goBiologicalProcess	[GO_BiologicalProcess:3600] peptidyl-serine phosphorylation
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [EntityWithAccessionedSequence:9977864] p-S21,T32,S43-ORF57 [cytosol] [Human herpesvirus 8]
internalReviewed	[InstanceEdit:9985769] Orlic-Milacic, Marija, 2026-03-26
isChimeric	FALSE
literatureReference	[LiteratureReference:9977863] Stability of structured Kaposi's sarcoma-associated herpesvirus ORF57 protein is regulated by protein phosphorylation and homodimerization
modified	[InstanceEdit:9978474] Stephan, Ralf, 2026-01-01 [InstanceEdit:9983303] Stephan, Ralf, 2026-02-21 [InstanceEdit:9985311] Stephan, Ralf, 2026-03-18 [InstanceEdit:9985776] Stephan, Ralf, 2026-03-26
name	Unknown kinase phosphorylates ORF57
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [EntityWithAccessionedSequence:9977867] p-S21,T32,S43,S95,S97-ORF57 [cytosol] [Human herpesvirus 8]
precedingEvent	[Reaction:9977857] CK2 phosphorylates ORF57 [Homo sapiens]
relatedSpecies	[Species:2671781] Human herpesvirus 8
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9977874] R-HSA-9977862.1
summation	[Summation:9977871] An unknown kinase phosphorylates HHV8 Post-transcriptional r...
(hasEvent)	[Pathway:9976073] Maturation/Activation of Immediate/Early HHV8 Proteins [Homo sapiens]
(precedingEvent)	[Reaction:9977877] p-ORF57 dimerizes [Homo sapiens]
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No pathways have been reviewed or authored by Unknown kinase phosphorylates ORF57 (9977862)