Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person RV-A NSP3 evicts PABPC1 from the translation initiation complexes

Class:Id	Reaction:9977823
_displayName	RV-A NSP3 evicts PABPC1 from the translation initiation complexes
_doRelease	FALSE
_timestamp	2026-01-21 22:27:42
authored	[InstanceEdit:9979788] Orlic-Milacic, Marija, 2026-01-21
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9977824] Orlic-Milacic, Marija, 2025-12-23
disease	[Disease:3134794] viral infectious disease
input	[Complex:72571] 43S complex [cytosol] [Homo sapiens] [Complex:156809] Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:156803] PABPC1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72557] EIF1AX [cytosol] [Homo sapiens]
modified	[InstanceEdit:9979789] Orlic-Milacic, Marija, 2026-01-21 [InstanceEdit:9979821] Orlic-Milacic, Marija, 2026-01-21
name	RV-A NSP3 evicts PABPC1 from the translation initiation complexes
negativePrecedingEvent	[NegativePrecedingEvent:9979808] Negative relationship: NSP3 promotes retention of PABPC1 in the nucleus
output	[Complex:156804] 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72557] EIF1AX [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9966113] NSP3 binds eIF4G [Homo sapiens] [Reaction:9966063] NSP3 binds RV-A mRNAs [Homo sapiens]
regulatedBy	[NegativeRegulation:9977822] Negative regulation by 'm7G(5')pppGm-RV-A-VP6-mRNA:NSP3 dimer:eIF4F:ZC3H7B [cytosol]'
relatedSpecies	[Species:9615053] Rotavirus A
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9977832] R-HSA-9977823.1
summation	[Summation:9977827] RV-A translation enhancer protein NSP3 simultaneously bin...
(hasEvent)	[Pathway:9974192] Rotavirus A (RV-A) host interactions [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by RV-A NSP3 evicts PABPC1 from the translation initiation complexes (9977823)