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Details on Person NSP2 inhibits DGAT1-mediated conversion of diacylglycerol to triacylglycerol

Class:Id	Reaction:9977035
_displayName	NSP2 inhibits DGAT1-mediated conversion of diacylglycerol to triacylglycerol
_timestamp	2025-12-16 15:23:02
catalystActivity	[CatalystActivity:76102] diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643660] diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane] Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9977032] Orlic-Milacic, Marija, 2025-12-16
disease	[Disease:3134794] viral infectious disease
input	[SimpleEntity:76103] DAG [cytosol] [SimpleEntity:75967] FACoA [cytosol]
modified	[InstanceEdit:9977053] Orlic-Milacic, Marija, 2025-12-16
name	NSP2 inhibits DGAT1-mediated conversion of diacylglycerol to triacylglycerol
output	[SimpleEntity:549167] TAG [cytosol] [SimpleEntity:76194] CoA-SH [cytosol]
precedingEvent	[Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate [Homo sapiens] [Reaction:75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) [Homo sapiens]
regulatedBy	[NegativeRegulation:9977029] Negative regulation by 'NSP2:DGAT1 [endoplasmic reticulum membrane]'
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9977039] R-HSA-9977035.1
summation	[Summation:9977052] Tetrameric diacylglycerol O-acyltransferase 1 (DGAT1) associ...
(hasEvent)	[Pathway:9974192] Rotavirus A (RV-A) host interactions [Homo sapiens]
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No pathways have been reviewed or authored by NSP2 inhibits DGAT1-mediated conversion of diacylglycerol to triacylglycerol (9977035)