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Details on Person Endoplasmic reticulum mannosidase trims terminal mannose from Man9GlcNAc2-VP7

Class:Id	BlackBoxEvent:9976456
_displayName	Endoplasmic reticulum mannosidase trims terminal mannose from Man9GlcNAc2-VP7
_doRelease	FALSE
_timestamp	2026-01-21 15:42:24
authored	[InstanceEdit:9979788] Orlic-Milacic, Marija, 2026-01-21
catalystActivity	[CatalystActivity:548874] mannosyl-oligosaccharide 1,2-alpha-mannosidase activity of MAN1B1 [endoplasmic reticulum membrane]
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9976454] Orlic-Milacic, Marija, 2025-12-11
disease	[Disease:3134794] viral infectious disease
input	[EntityWithAccessionedSequence:9976288] Man9GlcNAc2-VP7 [endoplasmic reticulum membrane] [Rotavirus A] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
isChimeric	FALSE
modified	[InstanceEdit:9976471] Orlic-Milacic, Marija, 2025-12-11 [InstanceEdit:9979789] Orlic-Milacic, Marija, 2026-01-21
name	Endoplasmic reticulum mannosidase trims terminal mannose from Man9GlcNAc2-VP7
output	[SimpleEntity:9976460] beta-D-mannose [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:9976453] Man8GlcNAc2-VP7 [endoplasmic reticulum membrane] [Rotavirus A]
precedingEvent	[BlackBoxEvent:9976266] Glucosidase II removes glucose residue from Glu1Man9GlcNAc2-VP7 [Homo sapiens] [BlackBoxEvent:9976263] CANX binds Glu1Man9GlcNAc2-VP7 [Homo sapiens]
relatedSpecies	[Species:9615053] Rotavirus A
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9976464] R-HSA-9976456.1
summation	[Summation:9976469] Mannose residues in the attached N-glycan of VP7 were report...
(hasEvent)	[Pathway:9821190] Maturation of Rotavirus A (RV-A) proteins [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9976472] VP7 folding and formation of disulfide bonds [Homo sapiens]
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No pathways have been reviewed or authored by Endoplasmic reticulum mannosidase trims terminal mannose from Man9GlcNAc2-VP7 (9976456)