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Details on Person Signal peptidase cleaves VP7

Class:IdReaction:9976166
_displayNameSignal peptidase cleaves VP7
_doReleaseFALSE
_timestamp2026-01-21 15:44:49
authored[InstanceEdit:9979788] Orlic-Milacic, Marija, 2026-01-21
catalystActivity[CatalystActivity:9833178] serine-type endopeptidase activity of (Signal Peptidase Complex) [endoplasmic reticulum membrane]
created[InstanceEdit:9976167] Orlic-Milacic, Marija, 2025-12-08
disease[Disease:3134794] viral infectious disease
input[EntityWithAccessionedSequence:9821523] nascent VP7 [endoplasmic reticulum membrane] [Rotavirus A]
isChimericFALSE
literatureReference[LiteratureReference:9976190] Signal peptidase complex mediates rotavirus VP7 processing and virion assembly
modified[InstanceEdit:9976181] Orlic-Milacic, Marija, 2025-12-08
[InstanceEdit:9976193] Orlic-Milacic, Marija, 2025-12-09
[InstanceEdit:9976200] Orlic-Milacic, Marija, 2025-12-09
[InstanceEdit:9979789] Orlic-Milacic, Marija, 2026-01-21
nameSignal peptidase cleaves VP7
output[EntityWithAccessionedSequence:9976165] VP7 signal peptide [endolysosome lumen] [Rotavirus A]
[EntityWithAccessionedSequence:9976195] VP7 [endoplasmic reticulum membrane] [Rotavirus A]
precedingEvent
relatedSpecies[Species:9615053] Rotavirus A
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9976169] R-HSA-9976166.1
structureModified[InstanceEdit:9976200] Orlic-Milacic, Marija, 2025-12-09
summation[Summation:9976176]

Using VP7 from the rotavirus A (RV-A) simian strain SA11,...

(hasEvent)[Pathway:9821190] Maturation of Rotavirus A (RV-A) proteins [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9821541] VP7 is N-glycosylated [Homo sapiens]
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No pathways have been reviewed or authored by Signal peptidase cleaves VP7 (9976166)