Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person vPK phosphorylates RPS6

Class:IdReaction:9975046
_displayNamevPK phosphorylates RPS6
_doReleaseFALSE
_timestamp2026-06-05 07:13:29
authored[InstanceEdit:9991228] Stephan, Ralf, 2026-06-04
catalystActivity[CatalystActivity:9976039] protein serine/threonine kinase activity of p-S-vPK [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9975085] Orlic-Milacic, Marija, 2025-11-28
crossReference[DatabaseIdentifier:9857128] RHEA:17990
disease[Disease:3134794] viral infectious disease
goBiologicalProcess[GO_BiologicalProcess:3601] protein phosphorylation
input[EntityWithAccessionedSequence:72381] RPS6 [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9975076] A viral kinase mimics S6 kinase to enhance cell proliferation
modified[InstanceEdit:9976040] Orlic-Milacic, Marija, 2025-12-05
[InstanceEdit:9978797] Stephan, Ralf, 2026-01-08
[InstanceEdit:9983303] Stephan, Ralf, 2026-02-21
[InstanceEdit:9991596] Stephan, Ralf, 2026-06-05
namevPK phosphorylates RPS6
output[EntityWithAccessionedSequence:9975062] p-S235,S236-RPS6 [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:70106] H+ [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
relatedSpecies[Species:2671781] Human herpesvirus 8
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9975118] R-HSA-9975046.1
structureModified[InstanceEdit:9976040] Orlic-Milacic, Marija, 2025-12-05
[InstanceEdit:9978797] Stephan, Ralf, 2026-01-08
summation[Summation:9975042] The serine/threonine protein kinase of the Kaposi sarcoma he...
(hasEvent)[Pathway:9975083] HHV8 Host Interactions in Lytic Infection [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by vPK phosphorylates RPS6 (9975046)