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Details on Person OAT2 isoform 2 imports endogenous metabolites

Class:Id	Reaction:9974600
_displayName	OAT2 isoform 2 imports endogenous metabolites
_doRelease	FALSE
_timestamp	2025-12-17 10:21:17
authored	[InstanceEdit:9974640] Stephan, Ralf, 2025-11-24
catalystActivity	[CatalystActivity:9974648] transmembrane transporter activity of SLC22A7 isoform 2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9974599] Stephan, Ralf, 2025-11-23
crossReference	[DatabaseIdentifier:9955301] RHEA:50985 [DatabaseIdentifier:9974639] RHEA:60369 [DatabaseIdentifier:9974662] RHEA:66337 [DatabaseIdentifier:9958549] RHEA:74541 [DatabaseIdentifier:9974658] RHEA:75373 [DatabaseIdentifier:9974632] RHEA:75789 [DatabaseIdentifier:9974665] RHEA:76209 [DatabaseIdentifier:9974664] RHEA:76213 [DatabaseIdentifier:9974655] RHEA:76217 [DatabaseIdentifier:9974656] RHEA:76221 [DatabaseIdentifier:9974646] RHEA:76225 [DatabaseIdentifier:9974647] RHEA:76233
input	[DefinedSet:9974622] SLC22A7 end. metabolite cargo [extracellular region]
internalReviewed	[InstanceEdit:9977118] Matthews, Lisa, 2025-12-17
isChimeric	FALSE
literatureReference	[LiteratureReference:561248] Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]) [LiteratureReference:9947196] Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function [LiteratureReference:561060] Isolation of a family of organic anion transporters from human liver and kidney [LiteratureReference:9974637] Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP [LiteratureReference:9974635] In vitro studies with two human organic anion transporters: OAT2 and OAT7 [LiteratureReference:9974666] Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression [LiteratureReference:9973753] Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins [LiteratureReference:9974641] Nicotinic acid transport into human liver involves organic anion transporter 2 (SLC22A7)
modified	[InstanceEdit:9974621] Stephan, Ralf, 2025-11-24 [InstanceEdit:9974636] Stephan, Ralf, 2025-11-24 [InstanceEdit:9977119] Stephan, Ralf, 2025-12-17
name	OAT2 isoform 2 imports endogenous metabolites
output	[DefinedSet:9974597] SLC22A7 end. metabolite cargo [cytosol]
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9974602] R-HSA-9974600.1
structureModified	[InstanceEdit:9974621] Stephan, Ralf, 2025-11-24 [InstanceEdit:9974636] Stephan, Ralf, 2025-11-24
summation	[Summation:9974631] Solute carrier family 22 member 7 (SLC22A7; aka Organic anio...
(hasEvent)	[Pathway:561048] Organic anion transport by SLC22 transporters [Homo sapiens]
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No pathways have been reviewed or authored by OAT2 isoform 2 imports endogenous metabolites (9974600)