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Details on Person TDPK phosphorylates ThDP to ThTP

Class:Id	Reaction:997381
_displayName	TDPK phosphorylates ThDP to ThTP
_doRelease	TRUE
_timestamp	2013-02-22 16:19:06
authored	[InstanceEdit:997388] Jassal, B, 2010-11-09
catalystActivity	[CatalystActivity:997383] thiamine-diphosphate kinase activity of TDPK [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:997388] Jassal, B, 2010-11-09
edited	[InstanceEdit:997388] Jassal, B, 2010-11-09
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:29480] ThDP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:997386] Enzyme system involved in the synthesis of thiamin triphosphate. I. Purification and characterization of protein-bound thiamin diphosphate: ATP phosphoryltransferase
modified	[InstanceEdit:1006138] Jassal, B, 2010-11-10 [InstanceEdit:3165246] Jassal, B, 2013-02-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TDPK phosphorylates ThDP to ThTP ThDP + ATP <-> ThTP + ADP
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:964965] ThTP [cytosol]
precedingEvent	[Reaction:196761] 2xTPK1:Mg2+ phosphorylates THMN [Homo sapiens] [Reaction:199626] SLC19A2/3 transport extracellular THMN to cytosol [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:994085] D'Eustachio, P, 2010-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104641] R-HSA-997381.2
summation	[Summation:997384] Thiamin triphosphate (ThTP) is believed to be synthesized fr...
(hasEvent)	[Pathway:196819] Vitamin B1 (thiamin) metabolism [Homo sapiens]
(precedingEvent)	[Reaction:965067] THTPA:Mg2+ hydrolyzes ThTP to TDP [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787946] Update Tracker - [Reaction:997381] TDPK phosphorylates ThDP to ThTP - v44:[modifyText]
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