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Details on Person UniProt:F5HIN0 ORF56
| Class:Id | ReferenceGeneProduct:9973296 |
|---|---|
| _chainChangeLog | chain:1-843 for 9973296 added on Fri Feb 20 2026 |
| _displayName | UniProt:F5HIN0 ORF56 |
| _timestamp | 2026-02-20 22:02:56 |
| chain | chain:1-843 |
| checksum | 89248BFCB7DBAB0E |
| comment | FUNCTION Essential component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.SUBUNIT Associates with the helicase and the primase-associated factor to form the helicase-primase factor.SUBCELLULAR LOCATION Requires the presence of the primase associated factor to properly localize in the host cell nucleus.SIMILARITY Belongs to the herpesviridae DNA primase family. |
| created | [InstanceEdit:9973335] Orlic-Milacic, Marija, 2025-11-14 |
| description | recommendedName: fullName evidence="1"DNA primase ecNumber evidence="1"2.7.7.- |
| geneName | ORF56 |
| identifier | F5HIN0 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding DNA replication Helicase Host nucleus Hydrolase Metal-binding Nucleotide-binding Reference proteome Transferase Zinc Zinc-finger |
| modified | [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | ORF56 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PRIM_HHV8P |
| sequenceLength | 843 |
| species | [Species:2671781] Human herpesvirus 8 |
| (referenceEntity) | [EntityWithAccessionedSequence:9973225] ORF56 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9981622] ORF56 [cytosol] [Human herpesvirus 8] |
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No pathways have been reviewed or authored by UniProt:F5HIN0 ORF56 (9973296)
