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Details on Person UniProt:Q2HR89 HELI
| Class:Id | ReferenceGeneProduct:9973288 |
|---|---|
| _chainChangeLog | chain:1-788 for 9973288 added on Fri Feb 20 2026 |
| _displayName | UniProt:Q2HR89 HELI |
| _timestamp | 2026-02-20 21:49:37 |
| chain | chain:1-788 |
| checksum | 6584683373CEF404 |
| comment | FUNCTION Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs. Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.SUBUNIT Associates with the primase and the primase-associated factor to form the helicase-primase complex.SUBCELLULAR LOCATION Belongs to the herpesviridae helicase family. |
| created | [InstanceEdit:9973335] Orlic-Milacic, Marija, 2025-11-14 |
| description | recommendedName: fullName evidence="1"DNA replication helicase ecNumber evidence="1"3.6.4.- |
| geneName | HELI ORF44 |
| identifier | Q2HR89 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding DNA replication Helicase Host nucleus Hydrolase Nucleotide-binding Reference proteome |
| modified | [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | HELI |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | HELI_HHV8P D0UZQ6 |
| sequenceLength | 788 |
| species | [Species:2671781] Human herpesvirus 8 |
| (referenceEntity) | [EntityWithAccessionedSequence:9973391] MetO-M401-OGlcNAc-HELI [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9981408] HELI [cytosol] [Human herpesvirus 8] [EntityWithAccessionedSequence:9981410] OGlcNAc-HELI [cytosol] [Human herpesvirus 8] [EntityWithAccessionedSequence:9981416] MetO-M401,OGlcNAc-HELI [cytosol] [Human herpesvirus 8] |
| (referenceSequence) | [GroupModifiedResidue:9981411] O-glycosylated residue (O-(N-acetyl-β-D-glucosaminyl) residue) at unknown position [ModifiedResidue:9981417] L-methionine sulfoxide at 401 |
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No pathways have been reviewed or authored by UniProt:Q2HR89 HELI (9973288)
