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Details on Person Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP

Class:Id	Reaction:997326
_displayName	Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP
_doRelease	TRUE
_timestamp	2018-01-02 20:37:53
authored	[InstanceEdit:909728] Garapati, P V, 2010-07-07
catalystActivity	[CatalystActivity:997310] protein tyrosine phosphatase activity of PTPN2-1 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643262] protein tyrosine phosphatase activity of PTPN2-1 [nucleoplasm] Identification of a nuclear Stat1 protein tyrosine phosphatase
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:997324] Garapati, P V, 2010-11-08
edited	[InstanceEdit:909728] Garapati, P V, 2010-07-07
input	[Complex:873824] p-STAT1 homodimer [nucleoplasm] [Homo sapiens] [SimpleEntity:113518] H2O [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:997325] Identification of a nuclear Stat1 protein tyrosine phosphatase [LiteratureReference:997315] The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3
modified	[InstanceEdit:998144] Garapati, P V, 2010-11-09 [InstanceEdit:998146] Garapati, P V, 2010-11-09 [InstanceEdit:9034197] Orlic-Milacic, Marija, 2018-01-02 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP
output	[EntityWithAccessionedSequence:997294] STAT1-1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:997294] STAT1-1 [nucleoplasm] [Homo sapiens] [SimpleEntity:113550] Pi [nucleoplasm] [SimpleEntity:113550] Pi [nucleoplasm] [SimpleEntity:113550] Pi [nucleoplasm] [SimpleEntity:113550] Pi [nucleoplasm]
precedingEvent	[BlackBoxEvent:873917] Translocation of STAT1 dimer to nucleus [Homo sapiens] [Reaction:873927] Release of STAT1 dimer from active receptor unit [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:933762] Abdul-Sater, AA, Schindler, C, 2010-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105100] R-HSA-997326.4
summation	[Summation:997289] The nuclear isoform of T cell protein tyrosine phosphatase (...
(hasEvent)	[Pathway:877312] Regulation of IFNG signaling [Homo sapiens]
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No pathways have been reviewed or authored by Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (997326)