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Details on Person UniProt:Q2HR83 ORF49
| Class:Id | ReferenceGeneProduct:9973251 |
|---|---|
| _chainChangeLog | chain:1-302 for 9973251 added on Fri Feb 20 2026 |
| _displayName | UniProt:Q2HR83 ORF49 |
| _timestamp | 2026-02-20 22:25:00 |
| chain | chain:1-302 |
| checksum | 0DBAE5A8B7A2E6AE |
| comment | FUNCTION Plays a role in the activation the host JNK/p38 pathways necessary for KSHV reactivation from latency and for viral replication. Induces transcriptional activation through host JUN of several ORF50-responsive promoters.SIMILARITY Belongs to the herpesviridae BBRF1 family. |
| created | [InstanceEdit:9973335] Orlic-Milacic, Marija, 2025-11-14 |
| description | recommendedName: Protein ORF49 |
| geneName | ORF49 |
| identifier | Q2HR83 |
| isSequenceChanged | FALSE |
| keyword | Reference proteome Viral latency Viral reactivation from latency |
| modified | [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | ORF49 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | ORF49_HHV8P |
| sequenceLength | 302 |
| species | [Species:2671781] Human herpesvirus 8 |
| (referenceEntity) | [EntityWithAccessionedSequence:9973175] ORF49 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9978962] ORF49 [cytosol] [Human herpesvirus 8] |
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No pathways have been reviewed or authored by UniProt:Q2HR83 ORF49 (9973251)
