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Details on Person UniProt:F5HG20 ORF66
| Class:Id | ReferenceGeneProduct:9973248 |
|---|---|
| _chainChangeLog | chain:1-429 for 9973248 added on Fri Feb 20 2026 |
| _displayName | UniProt:F5HG20 ORF66 |
| _timestamp | 2026-02-20 22:50:47 |
| chain | chain:1-429 |
| checksum | 4E56FD2AE070237E |
| comment | FUNCTION Participates in the expression of late viral mRNAs.SUBUNIT Interacts with ORF34.SUBCELLULAR LOCATION Mainly localizes in host nucleus and partially in host cytosol.INDUCTION Expressed during the early stages of lytic infection.DISRUPTION PHENOTYPE Deletion mutant shows mainly attenuated late gene expression and decreased virus production while viral DNA replication remains unaffected.SIMILARITY Belongs to the herpesviridae UL49 family. |
| created | [InstanceEdit:9973335] Orlic-Milacic, Marija, 2025-11-14 |
| description | recommendedName: Protein ORF66 |
| geneName | ORF66 |
| identifier | F5HG20 |
| isSequenceChanged | FALSE |
| keyword | Host cytoplasm Host nucleus Reference proteome |
| modified | [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | ORF66 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | UL49_HHV8P |
| sequenceLength | 429 |
| species | [Species:2671781] Human herpesvirus 8 |
| (referenceEntity) | [EntityWithAccessionedSequence:9973317] ORF66 [nucleoplasm] [Human herpesvirus 8] [EntityWithAccessionedSequence:9973384] ORF66 [cytosol] [Human herpesvirus 8] |
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No pathways have been reviewed or authored by UniProt:F5HG20 ORF66 (9973248)
