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Details on Person UniProt:F5HFQ0 gN
| Class:Id | ReferenceGeneProduct:9973180 |
|---|---|
| _chainChangeLog | signal peptide:1-17 for 9973180 added on Fri Feb 20 2026;chain:18-110 for 9973180 added on Fri Feb 20 2026 |
| _displayName | UniProt:F5HFQ0 gN |
| _timestamp | 2026-02-20 21:30:22 |
| chain | signal peptide:1-17 chain:18-110 |
| checksum | 468877D25B4B0173 |
| comment | FUNCTION Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity. Also plays a critical role in virion morphogenesis.SUBUNIT Interacts (via N-terminus) with gM (via N-terminus). The gM-gN heterodimer forms the gCII complex.INTERACTION When coexpressed with gM, localizes in the host trans-Golgi network.PTM O-glycosylated (By similarity). Contains alpha 2,6-sialic acid residues (By similarity). N-glycosylated.SIMILARITY Belongs to the herpesviridae glycoprotein N family. |
| created | [InstanceEdit:9973335] Orlic-Milacic, Marija, 2025-11-14 |
| description | recommendedName: fullName evidence="2"Envelope glycoprotein N |
| geneName | gN ORF53 |
| identifier | F5HFQ0 |
| isSequenceChanged | FALSE |
| keyword | Disulfide bond Host Golgi apparatus Host membrane Membrane Reference proteome Signal Transmembrane Transmembrane helix Viral envelope protein Virion |
| modified | [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | gN |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | GN_HHV8P |
| sequenceLength | 110 |
| species | [Species:2671781] Human herpesvirus 8 |
| (referenceEntity) | [EntityWithAccessionedSequence:9973249] GlcNAc-gN [trans-Golgi network membrane] [Human herpesvirus 8] [EntityWithAccessionedSequence:9973291] gN [virion membrane] [Human herpesvirus 8] [EntityWithAccessionedSequence:9973321] gN [plasma membrane] [Human herpesvirus 8] [EntityWithAccessionedSequence:9973361] gN [endoplasmic reticulum membrane] [Human herpesvirus 8] [EntityWithAccessionedSequence:9987195] GlcNAc-gN [viral envelope] [Human herpesvirus 8] |
| (referenceSequence) | [GroupModifiedResidue:9980700] N4-(N-acetylamino)glucosyl-L-asparagine (high-mannose N-glycan-yl group) at unknown position |
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No pathways have been reviewed or authored by UniProt:F5HFQ0 gN (9973180)
