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Details on Person Mouse Rnf220, an E3 ubiquitin ligase, mediates K63-linked po...
| Class:Id | Summation:9973051 |
|---|---|
| _displayName | Mouse Rnf220, an E3 ubiquitin ligase, mediates K63-linked po... |
| _timestamp | 2026-04-01 04:35:12 |
| created | [InstanceEdit:9973078] Orlic-Milacic, Marija, 2025-11-14 |
| literatureReference | [LiteratureReference:9973056] RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination |
| modified | [InstanceEdit:9986410] Orlic-Milacic, Marija, 2026-04-01 |
| text | Mouse Rnf220, an E3 ubiquitin ligase, mediates K63-linked polyubiquitination of mouse Olig1, leading to Olig1 protein stabilization and increased Olig1 transcriptional activity (Li et al. 2024). Two lysine residues of Olig1 polyubiquitinated by Rnf220 are K59 and K64 (Li et al. 2024). By UniProt Align tool, human and mouse OLIG1 share 88% amino acid sequence identity, while human and mouse RNF220 share |
| (summation) | [Reaction:9973077] Rnf220 mediates K63-linked polyubiquitination of Olig1 [Mus musculus] |
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No pathways have been reviewed or authored by Mouse Rnf220, an E3 ubiquitin ligase, mediates K63-linked po... (9973051)
