Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans

Class:IdLiteratureReference:9971688
_displayNameRepertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans
_timestamp2025-11-10 07:51:57
author[Person:9971678] IJspeert, Hanna
[Person:9971689] van Schouwenburg, Pauline A
[Person:9971674] Pico-Knijnenburg, Ingrid
[Person:9971691] Loeffen, Jan
[Person:9676754] Brugières, Laurence
[Person:9971666] Driessen, Gertjan J
[Person:9971685] Blattmann, Claudia
[Person:9971670] Suerink, Manon
[Person:9971673] Januszkiewicz-Lewandowska, Danuta
[Person:9971680] Azizi, Amedeo A
[Person:9971671] Seidel, Marcus G
[Person:9947319] Jacobs, Heinz
[Person:9971667] van der Burg, Mirjam
created[InstanceEdit:9971668] May, Bruce, 2025-11-10
journalFront Immunol
pages1913
pubMedIdentifier31507588
titleRepertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans
volume10
year2019
(literatureReference)[Reaction:9943321] UNG hydrolyzes 2'-deoxyuridine in DNA yielding an abasic site [Homo sapiens]
[Pathway:9968295] Somatic hypermutation of immunoglobulin genes by error-prone mismatch repair (MMR) [Homo sapiens]
[Reaction:9968296] MLH1:PMS2 makes a single-stranded nick near U:G mismatch [Homo sapiens]
[Pathway:9968297] Somatic hypermutation of immunoglobulin genes by error-prone base excision repair (BER) [Homo sapiens]
[Reaction:9968300] MSH2:MSH6 bound to U:G mismatch exchanges ADP for ATP [Homo sapiens]
[Reaction:9968305] MSH2:MSH6:ADP binds U:G mismatch in dsDNA [Homo sapiens]
[Reaction:9968306] MSH2:MSH6:ATP bound to U:G mismatch binds MLH1:PMS2 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans (9971688)