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Details on Person Formation of inner dynein arm d

Class:Id	BlackBoxEvent:9969546
_displayName	Formation of inner dynein arm d
_timestamp	2026-03-02 22:32:38
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9969544] Rothfels, Karen, 2025-10-22
input	[EntityWithAccessionedSequence:9969319] DNAH1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969291] DNAL1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969291] DNAL1 [cytosol] [Homo sapiens] [DefinedSet:201859] ACTB, ACTG1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969316] TTC29 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969318] ZMYND12 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9982645] Ciliary Motility: Regulation of Axonemal Dynein Motors [Book:9980618] Ishikawa, Takashi Organization of dyneins in the axoneme Dyneins Structure Biology and Disease in "Dyneins Structure Biology and Disease" [Book:9969852] King, Stephen M Composition and assembly of axonemal dyneins "Composition and assembly of axonemal dyneins" in Dyneins Structure Biology and Disease [LiteratureReference:9983831] Composition and function of ciliary inner-dynein-arm subunits studied in Chlamydomonas reinhardtii [LiteratureReference:9983861] Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein [LiteratureReference:9983859] The light chain p28 associates with a subset of inner dynein arm heavy chains in Chlamydomonas axonemes [LiteratureReference:9984016] A novel subunit of axonemal dynein conserved among lower and higher eukaryotes [LiteratureReference:9984022] Novel 44-kilodalton subunit of axonemal Dynein conserved from chlamydomonas to mammals [LiteratureReference:9983833] Chlamydomonas inner-arm dynein mutant, ida5, has a mutation in an actin-encoding gene [LiteratureReference:9983857] The dynein gene family in Chlamydomonas reinhardtii [LiteratureReference:9966975] Consensus nomenclature for dyneins and associated assembly factors [LiteratureReference:9983846] Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme [LiteratureReference:9983841] Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella [LiteratureReference:9984020] Cryoelectron tomography of radial spokes in cilia and flagella [LiteratureReference:9984029] Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella [LiteratureReference:9984026] The structural heterogeneity of radial spokes in cilia and flagella is conserved [LiteratureReference:9969716] TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella [LiteratureReference:9968975] The Role of Hsp90-R2TP in Macromolecular Complex Assembly and Stabilization [LiteratureReference:9969656] Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins
modified	[InstanceEdit:9969883] Rothfels, Karen, 2025-10-23 [InstanceEdit:9984046] Rothfels, Karen, 2026-03-02
name	Formation of inner dynein arm d
output	[Complex:9969320] inner dynein arm d [cytosol] [Homo sapiens]
regulatedBy	[PositiveRegulation:9969855] Positive regulation by 'TTC12 [cytosol]' [PositiveRegulation:9983849] Positive regulation by 'PIH1D1 [cytosol]'
regulationReference	[RegulationReference:9969884] Positive regulation by 'TTC12 [cytosol]' TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella [RegulationReference:9983851] Positive regulation by 'PIH1D1 [cytosol]' Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9969550] R-HSA-9969546.1
structureModified	[InstanceEdit:9969883] Rothfels, Karen, 2025-10-23 [InstanceEdit:9984046] Rothfels, Karen, 2026-03-02
summation	[Summation:9969882] Inner dyenin arm d is one of six monomeric IDAs that make up...
(hasEvent)	[Pathway:9969543] Assembly of the epithelial motile axoneme [Homo sapiens]
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No pathways have been reviewed or authored by Formation of inner dynein arm d (9969546)