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Details on Person DNAI3 binds DNAI4 and DNAI7

Class:Id	Reaction:9969523
_displayName	DNAI3 binds DNAI4 and DNAI7
_timestamp	2026-02-18 21:23:25
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9969522] Rothfels, Karen, 2025-10-22
inferredFrom	[Reaction:9969454] Dnai3 binds Dnai4 and Dnai7 [Homo sapiens]
input	[EntityWithAccessionedSequence:9969257] DNAI3 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969259] DNAI4 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9969258] DNAI7 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9968858] IC138 is a WD-repeat dynein intermediate chain required for light chain assembly and regulation of flagellar bending [LiteratureReference:9968953] The IC138 and IC140 intermediate chains of the I1 axonemal dynein complex bind directly to tubulin [LiteratureReference:9968830] Functional diversity of axonemal dyneins as assessed by in vitro and in vivo motility assays of Chlamydomonas mutants [LiteratureReference:9968998] Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat [LiteratureReference:9968932] Role of the Novel Hsp90 Co-Chaperones in Dynein Arms' Preassembly [LiteratureReference:9966975] Consensus nomenclature for dyneins and associated assembly factors [LiteratureReference:9968807] Cytoplasmic factories for axonemal dynein assembly [LiteratureReference:9968946] The Chlamydomonas IDA7 locus encodes a 140-kDa dynein intermediate chain required to assemble the I1 inner arm complex [LiteratureReference:9968955] The Mr 140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring [LiteratureReference:9969038] bop5 Mutations reveal new roles for the IC138 phosphoprotein in the regulation of flagellar motility and asymmetric waveforms [LiteratureReference:9968863] IC97 is a novel intermediate chain of I1 dynein that interacts with tubulin and regulates interdoublet sliding [LiteratureReference:9968849] IC138 defines a subdomain at the base of the I1 dynein that regulates microtubule sliding and flagellar motility [LiteratureReference:9968780] A novel ankyrin-repeat protein interacts with the regulatory proteins of inner arm dynein f (I1) of Chlamydomonas reinhardtii [LiteratureReference:9982656] Keeping an eye on I1: I1 dynein as a model for flagellar dynein assembly and regulation [LiteratureReference:9982676] Structural studies of ciliary components [LiteratureReference:9980592] Axonemal Dynein Arms [LiteratureReference:9982645] Ciliary Motility: Regulation of Axonemal Dynein Motors
modified	[InstanceEdit:9982762] Rothfels, Karen, 2026-02-18
name	DNAI3 binds DNAI4 and DNAI7
output	[Complex:9969261] DNAI3:DNAI4:DNAI7 [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9969524] R-HSA-9969523.1
summation	[Summation:9969054] DNAI3 (also known as WDR63), DNAI4 (WDR78) and DNAI7 (CFAP94...
(hasEvent)	[Pathway:9969543] Assembly of the epithelial motile axoneme [Homo sapiens]
(precedingEvent)	[Reaction:9969526] DNAI3:DNAI4:DNAI7 bind DNAH2 and DNAH10 [Homo sapiens]
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No pathways have been reviewed or authored by DNAI3 binds DNAI4 and DNAI7 (9969523)