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Details on Person Classical Monocyte (CD14++CD16-)

Class:Id	Cell:9968692
_displayName	Classical Monocyte (CD14++CD16-)
_timestamp	2026-04-16 03:49:39
cellType	[CellType:9968656] classical monocyte
created	[InstanceEdit:9968714] Senff-Ribeiro, Andrea, 2025-10-20
literatureReference	[LiteratureReference:9968681] Nomenclature of monocytes and dendritic cells in blood
markerReference	[MarkerReference:9986321] CCL2 [secretory granule lumen] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9984908] CCR2 [plasma membrane] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9984912] CCR2 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9985591] CCR5 [plasma membrane] Fractalkine preferentially mediates arrest and migration of CD16+ monocytes [MarkerReference:9985592] CCR5 mRNA [cytosol] SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset [MarkerReference:9968718] GPIN-CD14(20-345) [plasma membrane] Nomenclature of monocytes and dendritic cells in blood [MarkerReference:9968716] CD14 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9970921] 4xPalmC-CD36 [plasma membrane] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9970934] CD36 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9970933] CD86 [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9984920] CD163 [plasma membrane] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9984924] CD163 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9986319] CSF3 [endoplasmic reticulum lumen] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9985605] CX3CR1 [plasma membrane] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9985615] CX3CR1 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9985601] FCAR [plasma membrane] Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells [MarkerReference:9985600] FCAR mRNA [cytosol] Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes [MarkerReference:9970914] FCGR1A [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9970924] FCGR1A mRNA [cytosol] SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset [MarkerReference:9987350] HIF1A mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets [MarkerReference:9970861] HLA class II histocompatibility antigen, DR alpha chain precursor [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9984907] HLA-DRA mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9987351] ID1 mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets [MarkerReference:9986335] IL6 [endoplasmic reticulum lumen] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9987342] IL8 [endoplasmic reticulum lumen] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9987340] IL8 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9986320] IL10 [endoplasmic reticulum lumen] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9985529] ITGAM [plasma membrane] High-Content Immunophenotyping and Hierarchical Clustering Reveal Sources of Heterogeneity and New Surface Markers of Human Blood Monocyte Subsets [MarkerReference:9985525] ITGAM mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets [MarkerReference:9985621] ITGAX [plasma membrane] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9987363] NFE2 mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets [MarkerReference:9986615] S100A8 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9986590] S100A9 [cytosol] Identification of novel functional differences in monocyte subsets using proteomic and transcriptomic methods [MarkerReference:9986610] S100A9 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9985581] SELL [plasma membrane] Comparison of gene expression profiles between human and mouse monocyte subsets [MarkerReference:9985584] SELL mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9987359] TFEC mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets [MarkerReference:9987362] TGIF1 mRNA [cytosol] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets
modified	[InstanceEdit:9970950] Senff-Ribeiro, Andrea, 2025-11-03 [InstanceEdit:9982457] Senff-Ribeiro, Andrea, 2026-02-17 [InstanceEdit:9982460] Senff-Ribeiro, Andrea, 2026-02-17 [InstanceEdit:9984929] Senff-Ribeiro, Andrea, 2026-03-13 [InstanceEdit:9985533] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9985586] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9985597] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9985604] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9985618] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9985623] Senff-Ribeiro, Andrea, 2026-03-20 [InstanceEdit:9986332] Senff-Ribeiro, Andrea, 2026-03-30 [InstanceEdit:9986339] Senff-Ribeiro, Andrea, 2026-03-30 [InstanceEdit:9986567] Senff-Ribeiro, Andrea, 2026-04-02 [InstanceEdit:9986631] Senff-Ribeiro, Andrea, 2026-04-03 [InstanceEdit:9987347] Senff-Ribeiro, Andrea, 2026-04-13 [InstanceEdit:9987369] Senff-Ribeiro, Andrea, 2026-04-13 [InstanceEdit:9987454] Senff-Ribeiro, Andrea, 2026-04-16
name	Classical Monocyte (CD14++CD16-)
proteinMarker	[EntityWithAccessionedSequence:9986317] CCL2 [secretory granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:2976755] CCR2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:171279] CCR5 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:166033] GPIN-CD14(20-345) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:51645] 4xPalmC-CD36 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:179784] CD86 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:2168868] CD163 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9986316] CSF3 [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:2980688] CX3CR1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:6806318] FCAR [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:197835] FCGR1A [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:197588] HLA class II histocompatibility antigen, DR alpha chain precursor [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8956764] IL6 [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:9987343] IL8 [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:9986324] IL10 [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:202757] ITGAM [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:202764] ITGAX [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9626834] S100A8 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9626869] S100A9 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985582] SELL mRNA [cytosol] [Homo sapiens]
RNAMarker	[EntityWithAccessionedSequence:9984917] CCR2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985587] CCR5 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9968655] CD14 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9970937] CD36 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9984910] CD163 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985613] CX3CR1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985602] FCAR mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9970871] FCGR1A mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987361] HIF1A mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9984901] HLA-DRA mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987353] ID1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987344] IL8 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985528] ITGAM mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987352] NFE2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9986563] S100A8 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9986560] S100A9 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9985582] SELL mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987354] TFEC mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9987356] TGIF1 mRNA [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9968751] R-HSA-9968692.1
tissue	[Anatomy:9987452] blood
(cell)	[MarkerReference:9968716] CD14 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9968718] GPIN-CD14(20-345) [plasma membrane] Nomenclature of monocytes and dendritic cells in blood [MarkerReference:9970861] HLA class II histocompatibility antigen, DR alpha chain precursor [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9970914] FCGR1A [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9970921] 4xPalmC-CD36 [plasma membrane] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors [MarkerReference:9970924] FCGR1A mRNA [cytosol] SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset [MarkerReference:9970933] CD86 [plasma membrane] A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets [MarkerReference:9970934] CD36 mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9984907] HLA-DRA mRNA [cytosol] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets [MarkerReference:9984908] CCR2 [plasma membrane] Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets List all 38 refering instances
(input)	[CellDevelopmentStep:9968665] Classical monocytes generate intermediate monocytes [Homo sapiens]
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No pathways have been reviewed or authored by Classical Monocyte (CD14++CD16-) (9968692)